PSV Eindhoven followed up Sunday's win over AZ Alkmaar with a 7-0 mauling of Sparta Rotterdam.
Arouna Kone and Jefferson Farfan were Sparta's chief tormentors as they netted first-half braces to set PSV on their way to victory.
Veteran defender Michael Reiziger popped up 12 minutes from time to add a fifth and it opened the floodgates as Farfan completed his hat-trick and Timmy Simons completed the rout to heap more misery on the cellar dwellers.
PSV remain two points adrift of Ajax at the top of the table as Henk ten Cate's charges proved too good for ADO Den Haag.
Gabri set Ajax on their way to three points with a goal on 20 minutes and Wesley Sneijder secured victory with a strike just before the break.
Erik Nevland scored twice as Groningen's impressive start to the season continued with a home win over Excelsior.
Heracles Almelo came from behind to draw 1-1 with RKC Waalwijk, as Robbert Schilder's goal cancelled out an effort from Ruud Berger.
The game between NEC Nijmegen and Roda JC ended goalless.