Dutch Cup holders Twente sailed through to the third round of the KNVB Beker while there were also wins for PSV Eindhoven, Ajax, Waalwijk, Heracles Almelo and Den Haag.
Eredivise leaders Twente had no trouble disposing of Zwaluwen Vlaardingen thanks to a comprehensive 8-1 win on Wednesday evening.
Dutch Under-21 midfielder Steven Berghuis scored four of the goals for Co Adriaanse's side.
Meanwhile, PSV Eindhoven also racked up eight goals as they thumped VVSB with Moroccan midfielder Zakaria Labyad bagging a hat-trick.
Ajax, who have won the competition a record 18 times, recorded a 3-1 win at Noordwijkerhout , while Heracles Almelo overcame JVC Cuijk thanks to Glynor Plet's early effort.
Waalwijk also won away at Hilversum's Mandemakers Stadion thanks to a 3-0 victory while Den Haag completed another away win for the Eredivise sides with a 3-1 win at SVV Scheveningen.
In the all-Eredivise clash De Graafschap defeated Utrecht 4-3 in a penalty shoot-out after the game ended 1-1 after extra-time. Dulee Johnson gave the hosts the lead but Utrecht hit back through Australian youngster Tommy Oar on the stroke of half-time but the hosts eventually prevailed on spot kicks.
Other Second Round Results:
HBS Craeyenhout 2 Lisse 3
Argon 0 Almere City FC 2
Berkum 2 Veendam 0
De Treffers 3 HHC 2
FC Eindhoven 3 Emmen 1
Genemuiden 3 HSC 1
UNA 1 FC Volendam 3