Bayern Munich narrowed the gap on leaders Borussia Dortmund to three points by beating Nurnberg, while Hamburg and Augsburg claimed important wins at the bottom of the table
Bayern Munich took a step towards the UEFA Champions League semi-finals in midweek by beating Marseille 2-0 away from home in the first leg of their last-eight tie, but reclaiming the Bundesliga title remains just as high on their list of priorities.
Jupp Heynckes selected a strong line-up for the trip to Nurnberg and, after a frustrating first half ended goalless, Arjen Robben slotted home in the 69 minute to clinch a 1-0 victory.
Bayer Leverkusen lost for a fourth time in succession as Freiburg kept up their run of encouraging form with a 2-0 success at the BayArena.
Julian Schuster fired Freiburg ahead after just eight minutes and Daniel Caligiuri found the target on the hour mark to seal all three points.
Werder Bremen's hopes of qualifying for Europe suffered a blow as they went down to a surprisingly one-sided 3-0 defeat at home to Mainz.
Adam Szalai broke the deadlock for Mainz after 19 minutes and Eric Choupo-Moting added a further two goals in the second half
Kaiserslautern remain rooted to the foot of the table with time now running out to escape after losing 1-0 to fellow strugglers Hamburg.
Hamburg had slipped into the bottom three following a dismal run of form but they took the lead when Marcell Jansen struck after 28 minutes and Kaiserslautern could not respond.
Cologne replaced Hamburg in the relegation zone following a 2-1 defeat away to Augsburg at the Impuls Arena.
Koo Ja-cheol's opener in the 19th minute was cancelled out by a Lukas Podolski penalty on 42 minutes but Augsburg restored their advantage before half-time thanks to a spot-kick of their own that was converted by Nando Rafael.
Hertha Berlin remain in the bottom three after surrendering a lead at home to Wolfsburg to lose 4-1.
Levan Kobiashvili's opener was cancelled out by an own goal from Christoph Janker, before Patrick Helmes netted twice and Mario Mandzukic grabbed another to seal an emphatic victory for Wolfsburg.