Two late goals from Udinese striker Antonio Floro Flores poured yet more misery on nine-man Reggina in Serie A on Sunday.
Reggina looked to be heading for a hard-earned point at the Stadio Oreste Granillo but two second-half dismissals handed Udinese the momentum.
Maurizio Lanzaro was the first to receive his marching orders before Antonino Barilla was handed a second yellow card with 28 minutes remaining.
And Pasquale Marino's side made their numerical advantage count as Floro Flores struck twice in the final six minutes.
Bottom-of-the-table Reggina remain without a win since November and lie seven points adrift of safety with seven games remaining.