After winning the first leg, Udinese are very much in the driving seat in the tie, but Spalletti does not want complacency.
"If we don't prepare in the right way, then we risk losing and possibly elimination," said Spalletti.
Star man David Pizarro has been racing back from injury - and could make a return.
"I'll decide on the eve of the match," added Spalletti. "The most important thing is that David has recovered."