Juventus head into the latest round of Serie A matches in complete control of the title race.
With just four games remaining, the Turin giants are eight points clear at the top of the standings.
The Old Lady will need to attempt to put the disappointment of Thursday night's 2-1 defeat at Benfica in the Europa League behind them when they visit relegation-threatened Sassuolo on Monday, though.
A late goal from Benfica forward Lima handed the Portuguese champions the edge heading into next week's semi-final return leg at the Juventus stadium, the venue for this year's final.
"It was an unfair result," manager Antonio Conte said to Gazzetta dello Sport. "We are disappointed with the outcome considering the performance we handed.
"But we cannot be depleted, there is still the return leg left to play and qualification is wide open.
"We must now bounce back immediately and turn our attention to our game at Sassuolo.
"With regards to the league, we are not at the finish line yet and we just need to focus on ourselves and not on Roma."
Second-place Roma have won eight league games on the trot heading into Friday's home match against AC Milan.
The Eternal City giants will be under pressure to end Milan's five-game winning streak knowing that a defeat coupled with a Juve victory would see the league title head to Turin for a third straight season.
Inter Milan take on Napoli at the San Siro on Saturday knowing that if results go their way they will leapfrog Fiorentina into fourth place.
The Nerazzurri trail two points behind Fiorentina, who square off at Bologna a few hours before.
Inter can expect a stern test with Rafa Benitez's Napoli knowing that victory in Milan would ensure them of a third-place finish and the precious last Champions League qualifying spot.
Parma are five points adrift of Inter, who hold the last European qualifying spot, and travel to Sardinia to face Cagliari.
The Ducale club are sixth in the standings, level on 51 points with fellow European hopefuls Milan.
Torino host Udinese on Sunday looking to keep up their good run of form.
The Granata have collected seven points of a possible nine in their last three league games to climb to eighth place.
Atalanta and Genoa square off in Bergamo with both sides desperate to end the rot having each lost their past three league games.
Chievo lost 1-0 against Sassuolo last time out and hold a two-point cushion with respect to the drop zone.
They take on Sampdoria in Genoa eager to take a big step towards Serie A safety.
Livorno fans will be hoping the return of coach Davide Nicola to the Amaranto hotseat will inspire the Tuscan outfit to victory over Lazio on Sunday.
The Leghorn outfit sacked Domenico Di Carlo after last weekend's 3-0 loss at Milan and brought back Nicola just three months after he was shown the door.
Livorno are 19th in the standings, three points behind safety.
Sunday's match at Hellas Verona is a must-win game for bottom-side Catania. The Sicilian outfit are five points adrift of Sassuolo, who are 17th and hold the last position of safety.