Genoa president Enrico Preziosi has announced that Domenico Criscito will not stay at the club beyond the summer.
Criscito has spent most of his career with Genoa and has developed into one of the finest left-backs in Serie A, making 14 appearances for Italy.
However, Preziosi recognises that it is now time for the 24-year-old to embark on a fresh challenge elsewhere.
Napoli have been heavily linked with a move for Criscito and Preziosi admits such a switch could materialise, although he is ready to listen to offers from anyone.
"The boy will certainly leave," Preziosi told Radio Kiss Kiss. "He's been at Genoa for some time and it is only right that he moves on to a different club.
"A switch to Napoli? It has been discussed, but I don't see a great amount of interest from the Azzurri for Mimmo.
"As far as I am concerned, I am ready to negotiate and people know where I am."