Furious Roma are planning a formal complaint against officials following their treatment during Wednesday's 2-1 defeat at Brescia.
The clash marked another frustrating evening for last season's Serie A runners-up, who thought they were denied at least two clear penalties and believed Philippe Mexes won the ball outside the box when a spot-kick was awarded to the hosts and the defender was given his marching orders.
The club then felt they were victims of another unjust decision when tearful goalkeeper Julio Sergio was forced to play on in stoppage time despite suffering suspected ankle ligament damage because coach Claudio Ranieri had used all his substitutes.
The incident capped another miserable night for Roma, who are yet to record a win this term, and sporting director Daniel Prade revealed the club are furious with the match officials.
"It's not anger, it's something more," said Prade in a statement.
"We will forcefully ask that the officials are suspended, in 21 years of football I've never seen five episodes like that."
Meanwhile, defender Mexes could face a lengthy ban after his angry confrontation with a linesman during the clash.
Television pictures appeared to show his foul on Brescia man Eder took place just outside the area, but the hosts were awarded a penalty and Mexes landed a second yellow card.
The 28-year-old Frenchman lost his composure and had to be restrained by his team mates as he clashed with referee's assistant Nicola Ayroldi following his dismissal.
"I hear that a long ban could fall to Mexes but it's not fair," added Prade. "It was the referee that made our player lose his mind."