Villarreal forward Jose Mari is a major doubt for next week's UEFA Champions League clash with Arsenal.
The Spaniard sustained a knee injury in Wednesday's first leg defeat at Highbury.
Jose Mari picked up the knock in a tackle by Gilberto Silva and he was forced off with the problem ten minutes into the second half.
The former Atletico Madrid striker will not feature against Real Sociedad this weekend and Villarreal's medical staff will assess his fitness again next Monday.
Villarreal captain Quique Alvarez has also been ruled out of the clash with Sociedad because of an ankle problem, but he is expected to be fit in time to face Arsenal.