Chelsea, Manchester United and Celtic all face away games in the UEFA Champions League on what promises to be another thrilling night of European action.
Defending champions Chelsea were held to a 2-2 draw by Juventus at Stamford Bridge in their Group E opener and will now be targeting a first win of the campaign against Danish minnows Nordsjaelland, who are making their debut in the competition.
Nordsjaelland lost 2-0 to Shakhtar Donetsk last time out and the Ukrainians can strengthen their grip on top spot with another victory on Tuesday, although it will be no easy task as Juventus have started the new season where they left off last term in storming to the Serie A title.
Manchester United have not been quite as convincing during the early part of the campaign and Sir Alex Ferguson will be demanding an improvement from his players after a shock home defeat against Tottenham in the Premier League. A trip to Romania lies in store, and there will be no danger of underestimating a CFR Cluj outfit that knocked out Basel in qualifying before beating Braga in their first group game.
Braga must bounce back quickly to restore hopes of advancing in the competition, but Galatasaray are also in need of three points after losing to United and will fancy their chances on Turkish soil.
If Galatasaray are a formidable proposition at home, then so are Spartak Moscow. It is a long journey for Celtic to the Russian capital, where they will play on the artificial turf at the Luzhniki Stadium, but with two games against Barcelona to come next it will be important for Neil Lennon's men to try and come away with a positive result.
Barcelona were given a fright by Spartak and will be keen to put on more of a show in Portugal against Benfica, who held Celtic to a goalless draw in their opening fixture.
The two early pace-setters in Group F lock horns in Borisov, where BATE will be looking to follow up an impressive away win against Lille by defeating last season's runners-up Bayern Munich.
Meanwhile, in Spain, Valencia and Lille will be eager to settle any nerves and get their campaigns up and running.