Valencia midfielder David Albelda looks set to be sidelined until the middle of December with a knee injury.
The Spain international had to be stretchered from the pitch early in the second half of Valencia's Liga clash with Osasuna.
Tests will be carried out on Monday to confirm the extent of the injury, but team doctor Antonio Giner has already informed Spanish media that Albelda is likely to be out for between six and eight weeks.
Albelda joins defenders Carlos Marchena and Asier del Horno and midfielder Ruben Baraja on Valencia's growing injury list.
He could miss Valencia's next three UEFA Champions League matches against Shakhtar Donetsk, Olympiakos and Roma, as well as a key period in the Spanish domestic season.