Leaders Sevilla were left frustrated after a goalless draw at Villarreal.
Both sides had chances to score at El Madrigal on Saturday evening, but no end product was to be seen in the end.
The result means the Andalucian club now lead champions Barcelona by three points, but the Catalan giants now have two games in hand on Sevilla.
In the other Saturday game in La Primera, Atletico Madrid defeated Osasuna 1-0 at the Vicente Calderon.
Jose Ze Castro (83) scored the winner for Atletico, but the game will be remembered for Osasuna having four players sent off before the end.
Carlos Cuellar, Roberto Soldado, goalkeeper Ricardo and Raul Garcia were all given their marching orders by referee Vicente Lizondo Cortes.