Marseille took over as the new leaders of Ligue 1 courtesy of a 2-0 victory over Nantes, while Bordeaux saw off Le Havre to climb into second.
With Lyon not in action until Sunday, their title rivals took full advantage to increase the pressure at the top of the table.
Renato Civelli and Brandao were on target for Marseille in the space of five second-half minutes to secure all three points against struggling Nantes.
Bordeaux brushed aside bottom club Le Havre with the visitors securing the lead as early as the 12th minute through Yoann Gourcuff.
Souleymane Diawara added a second before the hour mark and Wendel claimed a late third against their lowly hosts.
Lille are up into third place in the table on the back of their 2-1 success at home to Grenoble with Michel Bastos' 12th-minute penalty setting the hosts on their way.
Robert Vittek added a second before the interval and Sandy Paillot's last-gasp response was nothing more than a consolation for the visitors.
Monaco saw off Nancy 1-0 thanks to Chu-Young Park's winner 20 minutes from time, while Rennes and Valenciennes played out a goalless draw as both sides ended the match with only 10 men.
Auxerre defeated Le Mans 2-0 on home soil after Ireneusz Jelen and Dariusz Dudka found the net in the opening stages of the first half.
Olivier Echouafni grabbed a late leveller for Nice as they squandered an early lead before securing a point at home to Caen.
Mahamane Traore fired the hosts into a sixth-minute lead before Vincent Hognon's own goal (65) and Nicolas Seube's effort (74) put the visitors ahead.