Lille coach Claude Puel has been dealt a blow after three of his players picked up injuries on the opening day of the season.
Abil Rami and Yohan Cabaye were both injured during the 0-0 home draw against Lorient on Saturday while Luis Alberto Yanes also suffered a problem.
Rami sprained his knee and is expected to be sidelined for around a month while Yanes, who plays with the reserves, has broken a bone in his foot and will need around two months to fully recover.
Finally, key midfielder Cabaye strained a thigh muscle. The injury, however, is not too serious and the 21-year-old should only miss two games in Ligue 1.