Newport County owner Les Scadding says it is a 'dream' to be involved in one of the Football League's 125th anniversary fixtures.
The matches, two from each of the three divisions, will be played on the opening weekend of the 2013/14 season.
One of the games is Newport County's match against Accrington Stanley at Rodney Parade and Newport owner Scadding cannot wait for the historical fixture.
Speaking to Sky Sports News, Scadding said: "It's fantastic and something you dream of. To be part of something which is unique is fantastic."
Newport secured a place in League Two after beating Wrexham in the Conference play-off final at the end of last season and Scadding says his club are ready for League football.
He added: "Preparations are going well. The pitch looks fantastic and it will be perfect for when the season starts.
"We couldn't have wished for anything better and we hope our fans will be out in full support.
"Wales is really buzzing. Swansea did a fantastic season, Cardiff got promoted to the Premier League and we return to league football after 25 years."
Accrington are also looking forward to the new season and in particular their opener in Wales. Chief executive Rob Heys explained to Sky Sports News what an honour it is to play the game.
Heys said: "It's fantastic. It goes back a long time to when we were a founder member of the Football League.
"It gives us great pride knowing we were ahead of teams like Liverpool, Chelsea and Manchester United.
"It's also good for us because we are an established Football League side now and playing a side like Newport, we don't feel like the new boys any longer.
"Of course we will wish them well when we see them but hope to take the three points."
The full 2013-14 fixture list will be released at 09:00 BST on Wednesday.