Wycombe's plot for promotion from League Two will begin at home to Morecambe on August 3.
The Chairboys, who had an inconsistent campaign last term, then head to AFC Wimbledon before hosting Football League newboys Mansfield on August 17.
They then head along the M40 to take on local rivals Oxford, with the return fixture on March 18.
Christmas is spent at home with games at Adams Park against Newport and Fleetwood on Boxing Day and December 29 respectively while they see in the new year at Exeter on January 1.
They face Northampton at home on Easter Saturday before heading to Fleetwood two days later and then sign off at home against Bristol Rovers.
Their campaign concludes with a trip to Torquay on May 3.