Charlton Athletic will hope to banish the memories of their last two home matches as Notts County face Steel City opponents for the second time in three days.
League One leaders Charlton have lost their previous two games at The Valley and, after drawing at Scunthorpe United at the weekend, will hope to recover from their little wobble with victory over in-form Yeovil Town.
Sheffield United are second on goal difference and, after Sheffield Wednesday won 2-1 at Notts County on Saturday, will hope to emulate their city rivals with three points at Meadow Lane.
Dave Jones has been quick to make an impact since taking charge at Hillsborough and the Sheff Wed boss is chasing a fourth straight win against struggling Walsall.
Huddersfield Town drew for the 11th time in 17 away games at the weekend and head to bottom club Chesterfield in search of a much-needed success.
Promotion rivals MK Dons also drew on their travels on Saturday and now return to home soil to host Leyton Orient, who beat Brentford at the weekend.
Carlisle United are outside the play-offs on goal difference and entertain Preston North End, who ended a run of six games without a win by beating Exeter City.
Stevenage are only a point adrift of the top six, but face a crunch game at home to Colchester United, who could yet make a late burst for the play-offs.
Rochdale moved off the bottom of the table by beating Oldham Athletic at the weekend and play host to a Tranmere Rovers outfit yet to taste defeat since Ronnie Moore returned as manager.
There are also two games with implications in the battle for survival as Exeter City and Wycombe Wanderers, who are both in the bottom four, meet at St James Park.
Meanwhile, Scunthorpe United boss Alan Knill returns to his former club Bury with both clubs needing the points to edge nearer to safety.
Bournemouth and Brentford both look destined for mid-table finishes and another season of League One football ahead of their date at Dean Court.
The same is true of Hartlepool United, although their Tuesday night opponents Oldham are not completely out of the woods just yet.