Tranmere begin the 2013/14 League One campaign with a trip to Walsall on August 3.
Ronnie Moore's men, whose promotion ambitions fell alarmingly by the wayside last season, then host Crawley before visiting Crewe on August 17.
Moore takes his side to former clubs Oldham on August 31 and Rotherham on October 22 while they head to Molineux to take on Wolves on November 26.
Christmas sees games at Shrewsbury on Boxing Day and Sheffield United three days later, with Wolves coming to Prenton Park on January 1.
Easter Weekend involves a lengthy trip to Gillingham before a home game with the Blades while their campaign ends with a home game against Bradford on May 3.