At the Keepmoat Stadium, Iain Hume opened the scoring for league leaders Doncaster before James Coppinger and Billy Paynter also beat the defences of Pools keeper Scott Flinders to wrap up the win.
The result keeps Rovers one point clear of Sheffield United at the top of the table following their 2-0 win at Oldham, while Hartlepool are still firmly in the relegation zone.
The Blades made sure Doncaster could not open up a gap at the top thanks to second-half goals by Michael Doyle and Dave Kitson in their victory at Boundary Park.
Swindon maintained their promotion hopes as they came from behind to claim a late 2-1 win at Coventry to stay in third.
The Sky Blues went ahead in the second minute through Franck Moussa and it took until the 86th minute for Swindon to level the scores through Andy Williams, before Darren Ward's last-minute header snatched all three points.
Tom Adeyemi's 70th-minute goal for Brentford saw them beat Scunthorpe 1-0 at Griffin Park and stay in fourth place ahead of Yeovil, who are also on 61 points, following their own 1-0 home win over Tranmere courtesy of Edward Upson's score.
Jamie Proctor scored a goal in each half for Crawley as they beat Bury 2-0 at Gigg Lane, while Alan Judge's first-half strike was enough for Notts County to see off 10-man Carlisle 1-0 at Meadow Lane.
Judge fired County ahead from 20 yards 10 minutes before the break, with Lee Miller sent off for Carlisle with only one minute of normal time left on the clock.
Portsmouth saw off a rally from Crewe to win 2-1 at Gresty Road but they remain rock bottom of League One.
Patrick Agyemang put Pompey ahead in the sixth minute before David Connolly doubled the visitors' lead on the half-hour mark.
Mathias Pogba pulled one back for Crewe in the second half, but Portsmouth held on to claim their sixth league win of the season.
Charlie MacDonald scored a goal in each half as Leyton Orient beat Bournemouth 3-1 at Brisbane Road.
Brett Pitman pulled a goal back for the Cherries in the 66th minute but Kevin Lisbie put the result out of doubt soon after.
Two goals within the first seven minutes saw MK Dons draw 1-1 against Preston at stadium:mk.
Adam Chicksen scored for the home side in only the second minute before William Hayhurst levelled for Preston five minutes later.
A Jabo Ibehre brace inspired Colchester to a 2-0 win at Stevenage.
Ibehre headed his first just after the hour mark before sliding in his second 10 minutes later as Colchester claimed a vital three points in their bid to stave off relegation.
Will Grigg scored a penalty and then fired another in open play as he helped Walsall to a 3-1 home win over Shrewsbury.
Grigg opened the scoring from the spot after Febian Brandy was fouled by Stephen McGinn before Craig Westcarr doubled Walsall's lead just after the break.
Grigg added his second for a three-goal cushion before David McAllister headed a consolation goal for the visitors.