Leyton Orient boss Russell Slade was left to rue a tackle by Tottenham's Danny Rose which looks to have robbed him of his captain.
Midfielder Stephen Dawson is unlikely to be fit to face Walsall on Saturday after he was injured during last weekend's pre-season friendly against Spurs.
"It's extremely doubtful that Dawson will be fit," Slade told the Os' official website.
"It was a poor tackle by Danny Rose really and unfortunately it was on the same ankle that gave him a slight problem the previous week.
"He's fighting against the clock and it's unlikely he'll make it."