Mark Hughes is uncertain if Stoke skipper Ryan Shawcross will be fit to face former club Manchester United on Saturday.
As a 19-year-old, Shawcross enjoyed 18 minutes of first-team action with United in the Carling Cup before moving to Stoke.
But he could miss out on a meeting with United after being unwell for much of the week.
Manager Hughes said: "Ryan has been ill all this week.
"He didn't train on Thursday and we will need to check him in the morning. I am reasonably confident that he will come through but we do have alternatives."
Hughes is also waiting on American right-back Geoff Cameron, whose calf injury prevented him from facing West Brom last Saturday.
Hughes added: "Geoff has trained. Hopefully he won't get a reaction."
Meanwhile, the Stoke boss has confirmed that another American, Brek Shea, could be leaving the Britannia Stadium on loan.
Shea joined from Houston Dynamo in January when Tony Pulis managed the Potters but has failed to make an impact under Hughes.
Hughes added: "We will look at the situation and if we feel an opportunity presents itself for Brek to go out on loan and play games at a decent club and it would benefit us, we will look at it."