Cardiff stretched their lead at the top of the table to seven points as they claimed a 3-0 victory over struggling Blackburn, with a last-gasp Peter Whittingham penalty sealing the triumph.
With second-placed Hull not in action until Tuesday, when they take on fellow promotion hopefuls Watford, the win allowed the Bluebirds to cement their status in pole position.
Sylvan Ebanks-Blake scored a double as Wolves emerged 3-2 winners in the derby clash at Birmingham to climb out of the drop zone, despite a scare as Wade Elliott netted a late penalty for the Blues.
A fourth-minute Michael Keane own-goal and a Chris O'Grady strike handed relegation-threatened Barnsley a much-needed 2-0 victory over free-falling Leicester at Oakwell.
Relegation candidates Sheffield Wednesday suffered a blow at rock-bottom Bristol City as the home side snatched a stoppage-time 1-1 draw through Sam Baldock.
Nottingham Forest narrowly retained their unbeaten streak under Billy Davies as a stoppage-time penalty from Lewis McGugan sealed a 1-1 draw at Burnley after Junior Stanislas had put the hosts in front.
Ten-man Blackpool edged a 1-0 victory over promotion hopefuls Crystal Palace at Bloomfield Road to propel the Seasiders away from the drop zone, with Matt Phillips netting an 85th-minute winner after Barry Ferguson had been sent off for a second yellow just before half-time.
The tussle between Millwall and Ipswich at The Den ended in a goalless draw as the two sides shared the spoils.
In Monday's late game, Jake Buxton grabbed a late winner as Derby came from behind to beat Leeds 2-1 at Elland Road and leave manager Neil Warnock to decide that it was time to part company with the Yorkshire club.