Henri Camara is set to return to action in Wigan's crucial game against Watford next Wednesday.
The Senegalese striker has been sidelined since picking up a knee injury in the 1-0 defeat to Sheffield United before Christmas.
In his absence Wigan have lost seven out of eight Premiership games and have plummeted to just above the relegation zone.
Camara was considered for the defeat to Arsenal after returning to training last week but Jewell decided to keep him up his sleeve until the game with Watford.
Victory over Watford would lift Wigan eight points clear of relegation rivals West Ham and Charlton, and Jewell believes Camara's return could help his side beat the drop.
"Henri will be in contention for the Watford game," Jewell told Wigan Today.
"That is his aim to try and get into the team, certainly into the 16.
"It is great to have him back training. He's been a big loss for us and can play a key part for us during the run-in."
Paul Scharner, meanwhile, who has also been out since December due to knee trouble, is closing in on a return to the first-team.
Jewell revealed: "Scharner is maybe two or three weeks away. When you look at our results, Paul has been a big miss for us.
"He gives us something different in midfield with his power, energy and strength."