Jonathan Woodgate and Julio Arca have both been ruled out of Middlesbrough's FA Cup fourth round replay with Bristol City - a game which you can see live on Sky Sports 1.
Arca featured in Boro's weekend defeat at Chelsea, but Woodgate missed the game after feeling a stiff hamstring following international duty with England.
Boro boss Gareth Southgate is not risking Woodgate and Arca is also being rested due to an ankle blow.
"I don't think he'll be fit," Southgate said of Woodgate.
"He's still quite tight in the hamstring and we've got to be quite protective of him.
"Jonathan is an outstanding player and I think any team in the country would miss him.
"He has a good chance for Saturday I would say but I'm not prepared to take a gamble."
On Arca, he added: "I'm unlikely to risk him, he's taken a few knocks in recent games but he's a tough little so and so.
"He's been so influential for us so it's not a decision I will take lightly."
One boost for Boro is that teenage star Lee Cattermole will feature having overcame a hamstring injury.
South Korean Lee Dong-gook will not be available to play as he was not registered in time for the original tie.
"Apparently if you're not signed in time for the original game you can't play in the replay," said Southgate.
"But he looks sharp in training so should we get through this game he comes into contention for Saturday."