Bayern Munich duo Arjen Robben and Toni Kroos will sit out the final UEFA Champions League group game against Manchester City on Wednesday.
Former Chelsea winger Robben, who has been struggling with a pelvic injury this season, will miss the game at the Etihad Stadium due to flu.
Germany international Kroos has also been laid low by flu and has stayed behind in Bavaria to recuperate ahead of the weekend's Bundesliga game against Stuttgart.
Even though they are assured of progression, captain Philipp Lahm is adamant the Bundesliga leaders would be doing everything possible to claim all three points against City.
"We can approach the game with a certain amount of calm," Lahm told the club's official website, "but we will do everything to ensure that we come home with the points.
"We are athletes and want to win every game."
The match has far greater importance for City, who need to win and hope Napoli fail to beat Villarreal to secure a top two spot in Group A.
Bayern defender Daniel van Buyten spent a loan spell at City in 2004 and he is expecting a hot atmosphere.
The Belgian said: "It's a fantastic stadium with fantastic fans who always get behind their team, even when they're 3-0 down.
"It'll be a hostile atmosphere. The fans will roar their team on. I think it'll be a good game for the spectators."
Van Buyten admits knocking big-spending City out of the Champions League at this stage could benefit the Germans in the latter rounds.
He added: "Manchester City have so much potential and excellent players. They could be nasty opponents later in the competition."