James McFadden looks set to be forced to sit out this weekend's Merseyside derby because of a hamstring injury.
The Everton forward limped out of Scotland's Euro 2008 qualifier against Lithuania on Wednesday.
He now appears likely to miss the game against Liverpool on Saturday, which will be a blow to both the player and manager David Moyes.
McFadden is yet to start a Premiership game this season but his impressive performances for Scotland recently had brought him into the reckoning for a starting place.
Moyes had hinted that the 23-year-old was in his plans for upcoming games but could have to change his thinking for this weekend's fixture.
Meanwhile, Lee Carsley believes Moyes is the man to orchestrate a derby win at Goodison Park.
The Toffees have won just once in the last 13 derbies, when Carsley scored the only goal in a 1-0 success, and the midfielder is confident of a repeat on Saturday.
"We won't just be going out there and hoping for the best," Carsley told icLiverpool.
"The manager is very big on systems and tactics and there certainly will be a thoroughly thought-through game plan."