William Gallas is set to miss Arsenal's Premier League clash against Stoke through injury while Emmanuel Eboue is also doubtful.
Both defenders featured in The Gunners' 4-4 draw with North London rivals Tottenham on Wednesday, but picked up knocks in the process.
Gallas, who scored in the epic clash, is struggling with a hamstring injury while Ivory Coast international Eboue has a knee injury.
Arsene Wenger has confirmed Arsenal will asses the extent of Eboue's injury on Friday, while Kolo Toure is on standby to fill in should Gallas miss out against The Potters.
"It looks like Gallas will be out and maybe Eboue too," he told the club's official website. "We'll assess him tomorrow.
"It is a little recurrence of the hamstring for William and for Manu it is his knee. He is not running properly at the moment. He still has pain there."