Wayne Rooney and Robin van Persie will again be missing when Manchester United host Swansea on Saturday evening.
Rooney has been sent for warm-weather training with a fitness coach in the hope his groin problem will heal in time for next weekend's trip to Chelsea.
But David Moyes gave no timescale when asked about Van Persie, who has played just twice in two months because of a thigh injury.
"Robin's going to be a little while," he said. "We'll do everything we can to get him back."
Injury kept Rooney out of United's last two games - an FA Cup exit against Saturday's opponents and defeat at Sunderland in the first leg of the Capital One Cup semi-final.
"It is the right time," Moyes said. "We have given it a chance to heal. He's away with his family and the coach. Hopefully we can get him fit to face Chelsea."
Another defeat this weekend would make it four in a row - an unprecedented run for the club in the Premier League era.
Moyes was in the market for new signings even before the latest injury news, and he said: "The plan and decisions won't change.
"It is difficult to get targets at this time. I have said that from day one. I have not said we wouldn't be doing it but it is difficult."
The Blues had two bids for Rooney rejected in the summer and there has been speculation that Mourinho is ready to pounce for the England international if United fail to qualify for the Champions League at the end of the season.
Mourinho responded to questions about Rooney at a press conference on Friday by shaking his head and insisting he was not prepared to speak about a player from a team Chelsea are scheduled to face at Stamford Bridge next Sunday.
"I don't want to speak about it," Mourinho said.
"We play Man United in a few days. I don't think it's nice to speak about a Man United player.
"You have to ask him (Rooney). You have to ask the player. And Man United because Man United has a contract with the player that doesn't end at the end of the season."
Watch Manchester United take on Swansea this Saturday evening, live on Sky Sports 1. Coverage starts at 5pm.
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