Manchester United goalkeeper Anders Lindegaard will be out for at least four weeks with an ankle injury, but David de Gea should be fit to face Chelsea on Sunday.
Lindegaard and De Gea both missed United's 2-0 victory over Stoke City in midweek through injury, prompting Sir Alex Ferguson to hand youngster Ben Amos his Premier League debut.
Denmark international Lindegaard's injury is the more serious and he is unlikely to be back in action for the reigning champions until March.
However, De Gea is expected to be available for the trip to Stamford Bridge, with Amos dropping back to the bench to provide cover.
"De Gea should be fit," said Ferguson. "It looks like Lindegaard will be out for at least four weeks, maybe even five or six. It's ankle ligaments.
"Ben Amos has been looking for his opportunity for quite a while and we wondered about sending him out of loan. But it's not easy when you're in Europe - you need three keepers. He did very well the other night."
Ferguson is also hoping Wayne Rooney, Nani, Ashley Young and Tom Cleverley will be in his squad, although the latter is unlikely to figure on Sunday.
Cleverley, who has been out since the end of October with an ankle problem, has instead been earmarked for an outing against Chelsea's reserve side on Monday.
The United boss added: "We're a bit better in terms of injuries. I hope Rooney, Nani, Cleverley and Young will all be in the squad.
"Rooney and Nani have trained for the last two days. It's more likely Tom will play against Chelsea reserves on Monday but he'll travel [on Sunday]."
Who should play in goal for Man Utd against Chelsea?
David de Gea