Edwin van der Sar, Gary Neville and Wes Brown will sit out Manchester United's UEFA Champions League tie at Celtic.
The United trio have not travelled with their team-mates to Glasgow ahead of Wednesday's Group E encounter at Parkhead.
The holders have confirmed that Dutch goalkeeper Van der Sar has been rested, rather than being left out due to injury.
England cap Ben Foster is expected to be given the nod to make his Champions League debut ahead of Polish shot-stopper Tomasz Kuszczak.
Van der Sar was left out of last week's 2-0 win over West Ham United, with Kuszczak taking the gloves, but Foster is due to make his first appearance of the season on Wednesday.
United boss Sir Alex Ferguson is also without Brown after the full-back failed to shake off an ankle knock which has kept him out of the last two matches.
Captain Neville has also been left in Manchester, so exciting Brazilian teenager Rafael da Silva looks set to start at right-back.
The only other injury absentees are midfield duo Owen Hargreaves and Paul Scholes as United look to book a place in the last 16 with victory over the SPL champions.