Former Tottenham striker Jermain Defoe scored twice on his Major League Soccer debut as Toronto FC won 2-1 at the Seattle Sounders.
Defoe took Jonathan Osorio's through ball in his path and finished low past Stefan Frei to open his account after 17 minutes, then latched on to an errant pass from the Sounders' Marco Pappa to bag his second seven minutes later.
Clint Dempsey pulled one back for the hosts midway through the second half.
"To score two goals in your debut, it's a dream," Defoe said. "To come here and to win was massive for us. Everyone's delighted - it was an important three points.
"I said to Jonathan, I said to him, 'when I make the runs, just look for me,' and he said, 'yeah, I'll look for you straight away.' It was an unbelievable pass. I've always worked on those situations, one-on-one with the goalkeeper. You have to be clinical."
Coach Ryan Nelsen added: "That was Jermain Defoe. Let's just say I'm not surprised. When the ball falls in those situations, he puts them away. That's why we brought him in. I was hoping he'd get in those scenarios and he got in them."
Matt Hedges netted a last-minute equaliser as FC Dallas claimed a 1-1 draw at Sporting Kansas City.
Aurelien Collin broke the deadlock after 81 minutes but Hedges struck late on to ensure the 2013 champions remained winless from their opening two games.
A late double from Victor Bernardez saw the San Jose Earthquakes rally from two goals down to draw 3-3 with Real Salt Lake.
Chris Wondolowski opened the scoring for San Jose in the seventh minute, but goals from Kyle Beckerman (11), Joao Plata (33) and Luke Mulholland (45) seemed to be sending them to defeat.
Bernardez pulled one back in the 75th minute, though, then netted a leveller in the closing moments to salvage a point.
A goal from Thierry Henry was not enough to give the New York Red Bulls victory over the Colorado Rapids.
The former France international opened the scoring in the 57th minute but substitute Vicente Sanchez levelled from the spot in the 72nd minute to ensure the match finished 1-1.
Sebastien Le Toux scored after 30 minutes to give the Philadelphia Union a 1-0 win over the New England Revolution, while Will Bruin's 40th-minute effort saw Houston overcome the Montreal Impact by the same scoreline and give the Dynamo their second victory from as many games.