Rangers have announced that Kyle Lafferty is likely to be sidelined until the end of February, while Steven Whittaker may require groin surgery.
Northern Ireland international Lafferty tore his hamstring just eight minutes into the Gers' 3-0 victory over Motherwell on Monday.
It was expected that he would miss a sizeable chunk of the season, and Rangers have confirmed that will be the case.
Gers boss Ally McCoist has also revealed that Whittaker is due to seek specialist advice on an injury which could keep him out of action for a similar amount of time.
He told Blues News: "It's not particularly good news for Kyle. He looks to have a tear in the hamstring and all indications were that was going to be the case judging by the way he pulled up.
"At this moment he is on crutches and we think probably six or seven weeks I'm afraid.
"(Nikica) Jelavic is a little bit better. I spoke with him and the groin injury is not as bad as it was but it's too early to say whether he will be available for our cup tie at Arbroath.
"Kirk Broadfoot is still struggling. His leg is heavily iced.
"Steven Whittaker is going down (to Manchester) next Tuesday or Wednesday to see the specialist regarding his groin problem and it will be determined then if he needs surgery.
"If there is anything needing done then hopefully it will be done immediately and we can get him back as quickly as possible."