Former Atalanta captain Cristiano Doni has been arrested in connection with another match-fixing probe in Italy.
Doni was among 17 people detained by police on Monday after an inquiry named "Last Bet" was carried out by Cremona prosecutors, who have uncovered a network linked with criminal organisations in Singapore.
Investigators are reportedly focusing on a number of Serie B games from the past two campaigns which could have been fixed.
Doni, who was banned from the game for three-and-a-half years this summer by the Italian Football Federation, was arrested on suspicion of attempting to destroy evidence.
"There were several elements that would have risked ruining the evidence and that led to the need for custodial measures," Cremona prosecutor Roberto Di Martino said in Gazzetta dello Sport.
"At the top of this organisation are men from Singapore, who are those who move the money, but the shareholders are divided from the West, to the Far East, to South America and they manage with their men how to change the outcome of football matches."
Former Italy international Luigi Sartor, ex-Serie B player Alessandro Zamperini and active players Carlo Gervasoni of Piacenza and Filippo Carobbio of Spezia were also arrested.
"This is not the end, but just a starting point," said Di Martino. "Let's hope it's a starting point to clean up the beautiful game that is football.
"One of the suspects has admitted that these operations have been going on for over 10 years."
There are also several Serie A matches from last season that are being reviewed, according to Marco Garofalo, head of police operations in Cremona.
He said: "The inquiry of the Cremona Prosecutors' Office are all relating to new games and relate to at least 20.
"The majority relate to Serie B games while there are three or four relating to Serie A although we don't have all the complete information as it is based on the testimony of one of the members of the criminal organisation."
This is the second betting inquiry in Italian football this year.
In June, numerous players and clubs were punished with bans and point deductions as a result of that investigation's findings.
Atalanta, who gained promotion to Italy's top flight this summer, began the Serie A campaign with a six-point penalty in connection to the June probe.