Martin Jol expects his Fulham side to claim a positive result against Wisla Krakow despite the absence of several key players.
Jol has opted to leave Danny Murphy, Bobby Zamora and Clint Dempsey in London for the trip to Poland, as he has an eye on their Premier League game against Everton on Sunday.
Dempsey and Zamora are being rested, while their captain Murphy misses the game with a knee injury.
Following the omission of the trio, Jol will be hoping that several fringe players take the opportunity to step into the breach their vacancies have created.
"Danny took a knock to his knee, which was pretty painful but hopefully he will be fit for selection on Sunday," he said.
"I spoke to the medical staff and we decided not to take a risk. Dempsey was left in London and Bobby was the same as I want him for Sunday, rather than risking him tomorrow because we have Andrew Johnson.
"[Mousa] Dembele is with us even though he had a little problem with his ankle and we have Orlando Sa, who can also play in attack."
He added: "We took a few younger players instead [rather than risking them] like Kerim Frei, Alex Smith and Marcel Gecov.
"That said, I do not have any concerns before the match. We have played with different teams before and have 22 good players, as well as a few younger players.
"Overall, we still have a very good team."