Arsenal manager Arsene Wenger says Sunday's North London derby will come too soon for injured defender Laurent Koscielny.
The Gunners boss is also waiting on the fitness of Theo Walcott and Gervinho, with a late decision to be made on both forwards ahead of the short trip to White Hart Lane.
All three players were left out of the midweek UEFA Champions League win over Olympiakos due to various knocks, and Wenger has revealed Koscielny is still struggling with an ankle problem.
"Koscielny looks to be definitely out for Sunday," Wenger told a pre-match press conference on Friday. "It looks short for him. He couldn't absorb any test today."
He added: "For Walcott and Gervinho a decision will be made on Saturday or Sunday. The most likely to be fit of the two looks to be Walcott."
Wenger confirmed that Yossi Benayoun and Sebastien Squillaci have recovered from knocks but says the latter is lacking match fitness and has not ruled out starting Alex Song in defence in his place.
He said: "Squillaci will not be fit enough to start the game. If I am tempted I can answer honestly 'yes'. Will I do it? Honestly I don't know yet."
Young winger Alex Oxlade-Chamberlain has been tipped for his first Premier League start after impressing on his Champions League debut in midweek, scoring the Gunners' opening goal.
Wenger says the teenager could be included but is giving nothing away over his line-up, adding: "He is a possibility to be in the squad. I haven't picked the team yet."
One player guaranteed not to feature is Thomas Vermaelen, whose recovery from an Achilles injury is taking longer than first anticipated.
"It will be a fraction longer than expected (before he returns)," added Wenger.
"He will not be straight back (in the squad) after the international break. It will be one or two weeks later."
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