Manchester United winger Antonio Valencia could make his return from injury in their FA Cup quarter-final.
United will host the winner of the Arsenal-Leyton Orient replay, with their Premier League title rivals expected to progress at home to League One Orient.
The Ecuador international has been sidelined since suffering a badly broken ankle in United's UEFA Champions League game with Rangers in September.
But the 25-year-old returned to training last week and Sir Alex Ferguson has confirmed that the cup game on March 12 has been pencilled in for Valencia's comeback.
"Antonio is training very well now," said the United boss.
"He is involved on the contact side and the signs are very encouraging. We expect him to be ready by the Arsenal cup tie."
Valencia was one of seven senior players missing as United flew out of Manchester for Wednesday night's Champions League game in Marseille.
United laboured to a 1-0 win over non-league Crawley in the FA Cup fifth round on Saturday but Ferguson is confident many of his injury absentees will recover in time for the second leg with Marseille in three weeks' time.
"Anderson got injured in the first half on Saturday," Ferguson added.
"We have sent him to Portugal to see a specialist he has dealt with over there. That will be two weeks - three at the most.
"Ryan Giggs should be okay for the Wigan game on Saturday, while Rio Ferdinand and Jonny Evans should be back for the Chelsea game next week.
"We have missed Park Ji-sung because he has been such a good player for us, but he should be back in two or three weeks."