Everton duo Jack Rodwell and Victor Anichebe are making their return from injuries for the reserves on Wednesday.
Highly-rated midfielder Rodwell has been out of action since the end of August after picking up an ankle problem in the defeat to Aston Villa.
Striker Anichebe has been missing since the final match of last season because of a knee injury but has been named as a substitute for the second string.
The pair will feature against Blackpool at Finch Farm as they look to build up their fitness.
Toffees boss David Moyes will be hoping the duo come through unscathed so that they can be available to his first-team squad soon.