Wigan manager Roberto Martinez has confirmed Gary Caldwell will not be risked at Newcastle on Saturday.
The central defender has not featured for the Latics since a hip operation in the summer but played 76 minutes for Scotland in last Friday's 1-0 defeat in Czech Republic, where he was switched to a defensive midfield role.
Following an agreement between Martinez and national team boss Craig Levein, Caldwell then sat out the 3-2 midweek defeat to Spain and he will also not be present when the Latics take on the Magpies in the Premier League on Saturday.
The Wigan boss said: "Gary will not be in the team to face Newcastle. There are different demands in the league.
"Craig Levein used him in a different position as well to his normal role at Wigan.
"Gary is not far away but I do not want to put him in a position that could see him perhaps being injured and also not being as good as he can be."
But Martinez was pleased with the way Caldwell slipped back into international football, saying: "To have that feeling of pride of playing for your country, Gary is a perfect example of that.
"He is a leader. Not even the most positive doctor expected him to be available. It was clear reward for his dedication, professionalism and hard work.
"It means he will be ready to play for us earlier than expected. Gary has been working so hard after surgery."