Last Updated at 11:34 am, April 22nd 2012
FULL TIME: Real Madrid have done the unthinkable and have won at the Camp Nou! The lead over Barcelona is now back to seven points. It's Barca's first home defeat of the season and they suffer back-to-back defeats for the first time since May 2009. Sami Khedira gave Jose Mourinho's side the lead after 17 minutes but Barca hit back through Alexis Sanchez's effort on 70 minutes. However, Cristiano Ronaldo won the game three minutes later to leave with all three points and move a step closer to the title.
SUBSTITUTION: Gonzalo Higuain replaces Karim Benzema for Real Madrid who has worked so hard this evening.
SUBSTITUTION: Mesut Ozil is replaced by Jose Callejon then.
Jose Callejon is ready to come on, but Real have this free-kick which they want to take first and it's headed away for a corner.
YELLOW CARD: Cristiano Ronaldo is too fast for Javier Mascherano and the former Liverpool man is booked for the late tackle.
Mazi Tweets: "I dont think Real will let this lead slip, the way Barca are playing, a draw would be a blessing for them."
SUBSTITUTION: Cesc Fabregas replaces Cristian Tello and Guardiola makes his final change.
YELLOW CARD: And now substitute Esteban Granero is booked for a late tackle on Lionel Messi.
YELLOW CARD: Mesut Ozil is booked for holding upthe play.
SUBSTITUTION: Adriano is replaced by Pedro as Pep Guardiola gambles!
SUBSTITUTION: Esteban Granero replaces Angel di Maria for Real Madrid.
GOAL: Barcelona 1 Real Madrid 2 (Cristiano Ronaldo 73).
GOAL: Barcelona 1 (Alexis Sanchez 70) Real Madrid 1.
SUBSTITUTION: Alexis Sanchez comes on to the field in place of Xavi.
Jordan emails in and says: "I am a major fan of Barcelona... And I'd love to see them win. Hopefully messi can pull something out the bag!"
Kieran Tweets: "I think that the way Barca are playing I think they will get one back but Ronaldo will score and settle it." Don't worry, you haven't missed anything because Pepe is on the ground rolling around in agony.
Chris Tweets: "Great game so far. This win would surely guarantee Madrid the league title, a huge knock for Barca's campaign." Absolutely spot on Chris!
Luke Tweets: "I think Barcelona will come back and win 2-1 with Messi with the both of them."
Sam emails me to say: "I love seeing Barca lose, hopefully it will upset Messi and he'll change his mind about coming to England!"
YELLOW CARD: Xabi Alonso makes a great challenge on Lionel Messi and referee Alberto Undiano Mallenco immediately takes his card out of his pocket. Shame!
Barcelona are now 9/4 to claim victory with SKY BET, who make Real Madrid 5/4 and the draw 2/1. My pre-match prediction of 1-1, which was 13/2, is now 3/1. Head now to www.skybet.com to place your bets.
HALF TIME: Sami Khedira's goal is the difference between the sides and it could also be the goal that takes Real Madrid towards the La Liga crown. Jose Mourinho has got his tactics spot on so far and are Barcelona on course for a second straight defeat in as many games? Should be an intriguing second half to come.
YELLOW CARD: Pepe is booked for a body check on Sergio Busquets.
Ben Tweets: "Don't agree that Ronaldo is better. He'll get more space now Barca are chasing too. Barca to turn it round 2nd half!"
Craig emails me to say: "Mourinho magic again, hope he stays at Madrid for the next few years, could make Madrid the very best in the world AGAIN! Ronaldo once again proves he is a bigger game player than Messi. Real to win 3-2 tonight."
GOAL: Barcelona 0 Real Madrid 1 (Sami Khedira 17).
YELLOW CARD: Sergio Busquets is booked for hacking Cristiano Ronaldo down after a superb turn of speed from the lightning quick winger.
Carlos Tweets: "Tonight Barcelona will beat Real Madrid. They're gonna win 3-1 with goals from Messi and Iniesta."
Lee emails me to say: "Don't mind who wins this but hope mourinho has told his team to nobble a few Barca players to help out Chelsea on Wednesday!"
Adam also thinks it's gonna be a 4-4!! He emails me to say: "A game between the two best managers and two best clubs out there this will be a classic 4-4. I like Tello and hope he bags a couple with Messi also scoring two goals. Couldn't care less who get's Madrid's long as it's not Ronaldo!"
While Maxi Tweets: "I predict a 4-4 thriller. A Ronaldo vs Messi battle! we can hope!"
Brizo says: "Real haven't beat Barca in the league since 2008 and that's not gonna change tonight. Messi-ah will rip them to bits 4-0 Barca." Confident call Brizo!
Alistair Tweets me to say: "El clasico day is better than Christmas for me!" Do you have Turkey while watching the match then Alistair?
Kahri Tweets me to say: "2-0 madrid with benzema and ronaldo scoring!"
While, Bamidele says: "Jose Mourinho will be 'parking the bus' today and hope to have a break on Barca. As boring as that may sound, it's gonna be a smart one if they close on a draw. Gap remains 4 pts."
Qasid is first to write in today and he says: "This is Nou Camp. This is Barcelona. Of course Barcelona will it, even though they're playing Real Madrid. Real Madrid have rarely done well against the Catalan giants. If Barcelona win, they'll keep the La Liga title race alive. Messi to score a brace, one of which will be a 'wonder' goal."
Spanish Primera BBVA