Baroness Tanni Grey-Thompson has been named on a three-person panel to assess the Lance Armstrong affair and the role of the International Cycling Union in the scandal.
The panel will also include retired British judge Philip Otton and Australian lawyer Malcolm Holmes as well as Paralympic great Grey-Thompson.
The trio will meet in London from 9-26 April and report their findings by 1 June.
The UCI asked Court of Arbitration for Sport board president John Coates to help create an independent commission to investigate suspicions raised by the US Anti-Doping Agency's damning report into widespread doping by Armstrong's teams during his seven Tour de France victories.
The governing body denies claims it covered up suspicious samples from Armstrong and took cash in exchange.
UCI president Pat McQuaid said: "The wide-ranging terms of reference demonstrate the Commission's determination to review fully the issues contained in the USADA report and I welcome that.
"The commission's report and recommendations are critical to restoring confidence in the sport of cycling and in the UCI as its governing body.
"We will co-operate fully with the commission and provide them with whatever they need to conduct their inquiry and we urge all other interested stakeholders to do the same.
"We will listen to and act on the commission's recommendations."
Armstrong did not cooperate with the USADA investigation and has been banned for life and stripped of all results from 1 August, 1998, including his seven Tour de France titles.