Hampshire's James Vince hit his second ton of the season, while Saeed Ajmal made an instant impact for Worcestershire.
Northamptonshire's Ireland international Niall O'Brien will join Leicestershire for the start of next season.
Ireland are dealing with an outbreak of illness in the camp on the eve of their do-or-die World Twenty20 meeting with West Indies.
Niall O'Brien hit 94 as Northants opened the CB40 season with a seven-wicket win over Leicestershire.
Cricket Ireland announced their squad on Saturday for their three match tour of Canada at the end of August.
Northamptonshire have suspended Niall O'Brien and stripped him of the vice-captaincy after a breach of team rules.
William Porterfield, Niall O'Brien and Boyd Rankin are all unavailable for Ireland's matches against West Indies A.
Niall O'Brien has delayed finger surgery, but Juan Theron will not be available for the start of Northants' FP t20 campaign.
Niall O'Brien wants to celebrate his 100th cap for Ireland by creating history and beating England on Tuesday.
Ireland captain Will Porterfield is set to earn his 100th international cap at the scene of one of his country's greatest moments.
Ireland secured a comfortable Twenty20 win against Afghanistan in the first Quadrangular series match in Sri Lanka.
Niall O'Brien smashed Northants to an eight-wicket victory over Surrey in Pro40 Division Two.
Niall O'Brien has set his sights on a shock victory over India after helping his side qualify for the Super Eights.
Hylton Ackerman's 139 set the platform for Leicestershire to claim a seven-run win over Northants in the FP Trophy.
Stephen Peters stroked an unbeaten 103 to take Northamptonshire to an eight-wicket victory over Ireland.
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