Craig Ervine has turned down a place in the Zimbabwe squad for their Test series with Bangladesh in order to play club cricket in England.
Ervine, who was the team's leading run-scorer on their recent tour of West Indies, does not have a central contract with Zimbabwe.
"It's disappointing not to be a part of this coming series," the batsman said on his Twitter account. "In life tough choices have to be made and this is one of them."
It is likely the 27-year-old Ervine will earn more money playing club cricket in England than playing for his country.
His older brother Sean, who signed a three-year contract extension with Hampshire this month, turned down the chance to go on the tour to the West Indies.
Zimbabwe will also be without injured trio Tino Mawoyo, Regis Chakabva and Chris Mpofu for the two home Tests against Bangladesh.
Pakistani-born batsman Sikandar Raza Butt is in line to make his debut in the first Test in Harare that starts on Wednesday while former captain Elton Chigumbura is set to return after being dropped.
Squad: Brendan Taylor (captain), Sikandar Raza Butt, Tendai Chatara, Elton Chigumbura, Michael Chinouya, Graeme Cremer, Kyle Jarvis, Timycen Maruma, Hamilton Masakadza, Shingirai Masakadza, Keegan Meth, Natsai Mshangwe, Tinotenda Mutombodzi, Richmond Mutumbani, Ray Price, Vusi Sibanda, Prosper Utseya, Brian Vitori, Malcolm Waller, Sean Williams