Pakistan head to neighbouring Bangladesh looking to improve an already strong record in the tournament, having lost in the 2007 final before winning the big prize in England in 2009.
The squad picked this time around includes a number of players involved in that Lord's success, including man-of-the-match Shahid Afridi, and their chances could well depend on his continued struggles with a groin problem.
Afridi was bothered by the injury during the recent Asia Cup in Bangladesh, which saw them lose to Sri Lanka in the final, and they have to hope he is 100 per cet by the time their tournament gets going at the end of the month.
Without him, their batting line-up looks steady but unspectacular and they would need to rely on matches being low-scoring affairs to compete with the best teams in the world - their tough qualifying group also including Australia, India and defending champions West Indies.
They head into the tournament having only played World Cup warm-up matches in T20 since December, when they struggled with the bat against Afghanistan and Sri Lanka in the United Arab Emirates but still managed to win two of their three matches,
If Afridi makes it, the pressure will be lifted a little from captain Mohammad Hafeez, who had a mixed Asia Cup campaign, and hard-hitting opener Ahmed Shehzad, whose patient century in their elimination game with Bangladesh set up Afridi's ferocious assault in the closing overs.
The inexperienced Sharjeel Khan and Sohaid Maqsood, plus brothers Umar and Kamran Akmal, provide the other main batting options along with Shoaib Malik who has been in and out of their plans in recent months.
Their bowling attack is full of experience but is more than likely to rely on the mystery spin of Saeed Ajmal, currently ranked No 2 in the world behind Sunil Narine.
Ajmal and the wily Hafeez, who is fifth in the ICC world rankings, will still need support from an inconsistent seam attack which is lacking the height and menace of Mohammad Irfan - he is sidelined by a hip injury suffered during a training session.
The awkward Sohail Tanvir and veteran Umar Gul - returning after a lengthy battle with knee trouble - provide Hafeez with options and there is also the promising Mohammad Talha and inexperienced Bilawal Bhatti if spin proves ineffective.
Squad: Mohammad Hafeez (capt), Ahmed Shehzad, Bilawal Bhatti, Junaid Khan, Kamran Akmal, Saeed Ajmal, Shahid Afridi, Sharjeel Khan, Shoaib Malik, Sohaid Maqsood, Sohail Tanvir, Mohammad Talha, Umar Akmal, Umar Gul, Zulifqar Babar.
Who will win the 2014 ICC World Twenty20?