Eoin Morgan will captain the England Lions in their two-day clash with Australia, which starts in Northampton on Friday.
The Middlesex batsman is one of a number of inclusions with senior experience but the only one who has recently been around the Test squad.
Australia had been due to face Northants at the County Ground, but the Lions will now fulfil the fixture with the Steelbacks on duty at Friends Life t20 Finals Day at Edgbaston.
There are three Lions debutants; Warwickshire bowler Keith Barker, Yorkshire opener Alex Lees and Sussex batsman Luke Wells, although the latter played within the England set-up for the Under-19 team.
National selector Geoff Miller said: "Northamptonshire's progression to the t20 Finals Day has presented us with a great opportunity to field a strong Lions team to face the Australian's at Wantage Road.
"We have looked to reward the players from the County circuit who have performed well this season and will look to push for places in future England squads with this fixture.
"With the Friends Life t20 Finals day running over the weekend of this fixture, we have been unable to select from any of the sides involved in that competition for obvious reasons, plus there are a number of other domestic fixtures that run very closely to this Lions game, so for practical reasons we had to recognise that a number of counties' players were unavailable.
"As is always the case with these fixtures, they are an excellent marker for judging the level of these players at a very high international standard and we look forward to seeing the team perform strongly against the Australian opposition."
Lions squad to face Australia
Morgan (Middlesex, capt), Ali (Worcestershire), Ballance (Yorkshire), Barker (Warwickshire), Jos Buttler (Somerset, wkt), Harris (Middlesex), Kerrigan (Lancashire), Lees (Yorkshire), Plunkett (Yorkshire), Stokes (Durham), Wells (Sussex)