Hampshire look to be firmly on course for an innings victory over Worcestershire after forcing their opponents to follow-on at the Ageas Bowl.
The Pears reached the end of day three on 159-5, still 192 runs short of making the home side bat again, having already been bowled out for 206 first time around.
Any hopes Worcestershire have of escaping with a draw rest on the shoulders of skipper Daryl Mitchell, who was unbeaten on 71 at the close of play.
Thilan Samaraweera kept his captain company during a third-wicket alliance worth 77, only for the former Sri Lanka international to fall for 27 right after a drinks break in the evening session.
Alex Kervezee and Neil Pinner also failed to make it through to stumps, leaving Mitchell relying on plenty of help from the tail if they are to avoid defeat on the fourth and final day.
They had lost five wickets for 47 runs in just over 20 overs in the morning session, meaning they fell well short of the 351 they required to avoid being asked to bat again by Hampshire skipper Jimmy Adams.
Resuming on 159-5, Pinner became the first to go when he went lbw to James Tomlinson for 29. Wicketkeeper Michael Johnson followed soon after, clean bowled by Sean Ervine, to leave the score at 189-7.
England spinner Danny Briggs struck in his first over of the morning, trapping Gareth Andrew lbw for five, and he also dismissed Richard Jones for seven.
Ervine (2-20) had last man Alan Richardson caught by George Bailey to give Adams the opportunity to ask Worcestershire to have another go.