Ian Bell continued his fine start to the season with a century for Warwickshire but his England colleague Joe Root's Yorkshire return did not go to plan.
Bell's 122 underpinned Warwickshire's first innings total of 263 after they had been sent in by Nottinghamshire in lively conditions on day one at Trent Bridge.
He struck 18 fours and two sixes during a 148-ball contribution and now has 400 runs in five innings this summer. Opener William Porterfield's 56 was the only other score of note in an innings lasting 72.2 overs.
Bell, who now has 47 first-class hundreds, was eventually ninth out, one of Nottinghamshire seamer Andy Carter's 5-55.
The quality of Bell's performance was put in perspective as Nottinghamshire stumbled to 43-6 at stumps, still 220 behind.
Warwickshire fast bowler Chris Wright took out three of the top four in compiling figures of 3-7 from eight overs, while nightwatchman Luke Fletcher was run out from the final ball of the day.
Meanwhile, Root was passed fit to return from a broken thumb and replaced Andrew Gale - both at No 4 in the batting order and as captain - for Yorkshire's trip to Lord's to take on Middlesex.
Root lost the toss and made a five-ball duck as Yorkshire were bowled out for 178, No 8 Liam Plunkett's 56 not out the top score in their innings.
Steven Finn trapped Root lbw as he continued his rehabilitation after a difficult Ashes tour with 4-50, while his fellow Middlesex seamers Tim Murtagh (3-48) and James Harris (3-42) claimed three wickets each.
Middlesex reached 64-3 in reply at stumps, trailing by 114. Jack Brooks accounted cheaply for both openers, Sam Robson and Chris Rogers, in his opening spell, while Eoin Morgan is 24 not out overnight.
It was also a difficult day for batsmen at Wantage Road, where 18 wickets went down on an opening day that saw Northamptonshire emerge 14 runs ahead of Lancashire.
Lancashire started the post-Peter Moores era by being dismissed for 119 in 44 overs, No 11 James Anderson's 28 the top score.
The home seam attack shared the wickets around, including three each for Azharullah (3-35) and Steven Crook (3-26).
It was a similar story for Lancashire's bowlers later in the day, Northants closing on 133-8 in reply. England international Anderson took 5-37 from 14 overs, the 30th five-wicket haul of his first-class career.
At Hove, Somerset reached 83-3 in the 32 overs possible after being asked to bat by early Division One leaders Sussex.
Marcus Trescothick and Nick Compton put on 78 for the second wicket after Somerset lost Chris Jones for a duck when play got under way at 4.30pm.
But Compton (41) and nightwatchman Jamie Overton both departed late on, leaving Trescothick 39 not out.
Sussex seamer Chris Jordan (2-30) accounted for Jones and Overton, while Steve Magoffin (1-19) had Compton caught behind.