Will Smith's patient 153 put Durham on course for their second win of the season after dominating the third day against Nottinghamshire at Trent Bridge.
The visitors extended their first innings total to 471, a lead of 151, before reducing their hosts to 145-5 by stumps, with Mark Wood taking three wickets.
Smith was eventually dismissed for 153 after his marathon stay at the crease had been extended to almost eight and a half hours, departing to the spin of Samit Patel, aided by a sharp diving catch at mid on by Luke Fletcher.
Phil Mustard had been the only other Durham batsman to fall during the morning session, edging behind to give Stuart Broad his fourth wicket of the innings.
Nottinghamshire were then made to wait for a further 26 overs before collecting the final two wickets to fall, as a further 115 runs were added.
Alex Hales' disappointing match continued at the start of Nottinghamshire's second knock. Dismissed for just two in the first innings, he failed to score when the home side batted again, losing his middle stump to Chris Rushworth.
Wood then took centre-stage with three quick wickets to tilt the balance of the match even more firmly towards his side.
Ed Cowan was caught behind, having put on 76 with Michael Lumb for the second wicket, James Taylor was given out lbw after shuffling across his stumps and Samit Patel fenced a short-pitched delivery to slip.
Steven Mullaney nudged Breese into the hands of Paul Collingwood just before stumps, leaving Michael Lumb unbeaten on 77 and his side still six runs away from making Durham bat again.