England team director Andy Flower has confirmed Eoin Morgan will miss the World Cup with a broken finger.
Morgan, whose place in the side will now be taken by Essex's Ravi Bopara, suffered a serious fracture to the middle finger on his left hand.
And although it was hoped the 24-year-old would be able to play some part in the tournament in the Indian sub-continent, Morgan now needs surgery on the finger.
Flower said: "Eoin Morgan won't be going to the World Cup.
"He needs his finger operated on and that is a serious loss for us. He has been a very influential limited overs performer for us since he joined the England team.
"But Ravi Bopara, who is an exciting young cricketer in his own right, is going to be joining us.
"He is going to be flying back from the West Indies where he is with the Lions set-up. He will be arriving back in the country tomorrow morning and joining us on the flight to Dhaka."
The absence of Morgan will be a big loss for England, with the Middlesex batsman having become a key figure in the limited overs side.
Morgan, who has scored 1,094 ODI runs at an average of 38.08, played a key role in the ICC World Twenty20 success and has gained a reputation as a dangerous middle order batsman.
However Flower has backed Bopara to rise to the challenge. "No one is irreplaceable and as I have said Ravi is a very talented player," added Flower.
"He will also bring a bit of medium pace bowling that will help out the captain in those middle overs in the sub-continent.
"We are confident that the 15 guys that we have got out there can gel together and perform powerfully."
While Morgan will miss out, Flower admitted there was "good news" over the rest of England's injured players, with Graeme Swann, Tim Bresnan, Ajmal Shahzad, Paul Collingwood, Stuart Broad and Chris Tremlett having all picked up knocks of varying seriousness in Australia.