Ireland will be missing a number of key players for their visit to Canada at the end of August.
Cricket Ireland announced their squad on Saturday for the trip, in which they will play two one-day internationals and an Intercontinental Cup match.
All-rounder Alex Cusack will not join the tour party due to a long-standing muscular injury for which he is due to undergo surgery. His recovery is expected to take around six weeks.
Niall O'Brien also misses out following an operation on his finger, but the Northamptonshire wicketkeeper is expected to resume playing before the end of the season.
And skipper William Porterfield, together with seamer Boyd Rankin, have been retained by their respective counties Gloucestershire and Warwickshire.
Surrey keeper Gary Wilson has also been held back by his domestic employer for the Intercontinental Cup match but has been released for the ODIs
There is better news for all-rounder Andre Botha, who has recovered from a stress fracture and makes the squad, which will be captained by Trent Johnston.
And Phil Eaglestone, who has been suffering from a side strain, has also been passed fit for the trip.
Ireland Squad: Trent Johnston (c), Andre Botha, George Dockrell, Phil Eaglestone, Allan Eastwood, Nigel Jones, Rory McCann, John Mooney, Kevin O'Brien, Andrew Poynter, Paul Stirling, Albert van der Merwe, Andrew White, Gary Wilson (ODI's only).