Sri Lanka have rested left-arm spinner Rangana Herath from the first two one-day internationals against Bangladesh.
Former captain Mahela Jayawardene was also not considered for selection for the two games at Hambantota on March 23 and 25 because of a finger injury.
Opening batsman Tillakaratne Dilshan will have to undergo a fitness test after he suffered a strain to his upper thigh during the second Test in Colombo on Sunday and was sent for a precautionary scan.
However Sri Lanka manager Michael de Zoysa is optimistic Dilshan will be available.
"Dilshan will be fit to play in the one-day series. He warmed up today with the rest of the team and showed no signs of any discomfort," said De Zoysa on Monday.
There are three newcomers in the 16-man squad - batsmen Kithuruwan Vithanage and Angelo Perera and left-arm spinner Sachitra Pathirana.
Vithanage made his Test debut against Bangladesh at Galle in the first Test of the current series and scored a half-century.
Off-spinner Sachithra Senanayake has been recalled to the squad for his first ODI since August 2012.
Squad: Mathews (capt), Chandimal, Dilshan, K Perera, Sangakkara, Thirimanne, Mendis, T Perera, Kulasekara, Malinga, Senanayake, Tharanga, Vithanage, A Perera, Eranga, Pathirana.